CPS Disc Centrifuge UHR Particle Size Analyser

The CPS DC24000 UHR is an ultra high resolution particle size analyser with unparalleled resolution accuracy, even when measuring nanoparticles less than 100nm. With clean separation of narrow peaks that differ in size by as little as 2%, the CPS DC24000 UHR uses Differential Centrifugal Sedimentation (DCS) to accurately size, detect and measure small changes in particle size.

It is also used to measure nanoparticle coating thickness, ideal for a range of applications including work with gold and silver nanoparticles.

Key Features:

  • Dynamic Balancing Module – displays disc speed, internal temperature and warns if the system is unbalanced, ensuring instrument longevity
  • High sensitivity – min. detection limit below 10-8 active sample for narrow peaks, allows small sample size
  • Highly reproducible results
  • Dynamic range capability – >1000 for measurement of broad and multimodal distributions
  • Measurement of particles of virtually any density
  • Extensive data reporting options – including multiple distribution overlays

As exclusive distributor for the UK and Ireland, Analytik is proud to supply the CPS DC24000 UHR from CPS Instruments Europe. Through Analytik, you’ll have access to our team of experts to help develop your application and get the most out of your investment.

For more information, or to discuss your requirements with a product specialist, please call us on +44 (0)1954 232 776 or email info@analytik.co.uk.

Description

CPS Disc Centrifuge UHR: A high resolution particle size analyser

The CPS DC24000 UHR is an effective particle size analyser for ultra high resolution, high accuracy particle sizing. Highly poly-dispersed particles can be measured in the size range of ~3.0nm to ~60 microns, at 2 to 10 times better resolution than any other particle sizing instrument, regardless of measurement technique.

Utilising Differential Centrifugal Sedimentation (DCS), the CPS Disc Centrifuge UHR offers the unique ability to resolve very close multimodal particle distributions and to distinguish extremely small shifts in particle size. Rather than using a predictive algorithm, the instrument physically separates the particles and then measures them as they pass a light source detector – providing full characterisation in real time.

Key Features:

  • Ultra high resolution particle sizing  with clean separation of narrow peaks that differ in size by as little as 2%
  • Able to detect and measure very small and subtle changes / differences in particle size
  • Able to measure / monitor nanoparticle coating thickness
  • In-built PC: the display shows the actual disc speed, internal temperature and it will show a user if the system is unbalanced
  • Dynamic Balancing Module ensures instrument longevity
  • Very high sensitivity; minimum detection limit below 10-8 gram active sample for narrow peaks
  • Highly reproducible results
  • Dynamic range capability >1000 for measurement of broad and multimodal distributions
  • Measurement of particles of virtually any density
  • Wide range of data presentation options, including multiple distribution overlays

Interested in the CPS DC24000 UHR? Request a quote or call us on +44(0)1954 232 776 to discuss your requirements.

Applications

PharmaceuticalResolve Aggregates and Agglomerates

  • Gold and silver nano-particles (coated and/or uncoated)
  • Virus particles/virus-like particles
  • Cells (culture) and cell fragments
  • Protein clusters
  • Liposomes
  • Particles in diagnostic tests
  • Micro-encapsulated drugs

ChemicalGold Particles Analysis

  • Polymer latexes and emulsions
  • Fillers (CaCO3, clay, barites, etc.)
  • SiO2 dispersions
  • Abrasives (of all types)
  • Impact modifier particles
  • Oil emulsions
  • Carbon nanotubes
  • Quantum dots
  • Metals and metal oxides

Printing and PaintingInk Pigments Analysis

  • Pigments – water and oil based
  • Micro-fibre paint viscosity modifiers
  • Printer/copier toner powders
  • Inkjet inks
  • Carbon black
  • Magnetic iron oxide

Semiconductor

  • Micro-abrasives
  • CMP compounds for integrated circuits

Others

  • Micro-spheres
  • Agglomeration patterns
  • Starch/flour particles

Videos

Differential Centrifugal Sedimentation with the CPS Disc Centrifuge

Particle Size Analysis Theory and Instrumentation

How to run samples on the CPS Disc Centrifuge UHR

Nanoparticle Size Analysis using the CPS Disc Centrifuge UHR

Using Differential Centrifugal Sedimentation for Particle Size Characterisation

Downloads

PDF Icon CPS Disc Centrifuge UHR Datasheet

PDF Icon An Introduction to Differential Centrifugal Sedimentation (DCS) Whitepaper

PDF Icon CPS Disc Centrifuge Service & Support Brochure

PDF Icon Particle Sizing: Are you getting the full picture?

Technical/Application Notes

PDF Icon Comparison of Laser Diffraction and DCS

PDF Icon Quantitative analysis of nanoparticles using DCS

PDF Icon Carbon nanotubes: Analysis of CNTs using the CPS Disc Centrifuge ‘UHR’

PDF Icon Latex and nanocomposite particle sizing: Advantages offered by the CPS Disc Centrifuge

PDF Icon Bio nanoparticle sizing: Analysing growth in real time with the CPS Disc Centrifuge

PDF Icon Characterising coating thickness for gold and silver nano-scale drug delivery

PDF Icon Adenovirus particles: Monitoring the production and purification process

PDF Icon Filter testing: Determination of pore size distribution using the CPS Disc Centrifuge

News & User Stories

PDF Icon Analytik reports on Scott Bader using the CPS Disc Centrifuge UHR analyser

PDF Icon Analytik report on use of CPS Disc Centrifuge system for characterising nanoparticles at the University of Liverpool and University College Dublin

PDF Icon Analytik reports on how the Food & Environment Research Agency used the CPS Disc Centrifuge analyser to study engineered nanoparticles

PDF Icon Analytik report on use of the CPS Disc Centrifuge for measurement of nanoparticles by the NPL

PDF Icon Analytik reports on the use of the CPS Disc Centrifuge system at the National Physical Laboratory

PDF Icon Analytik reports on the University of Sheffield using the CPS Disc Centrifuge for particle characterisation

PDF Icon Analytik report on work at the University of Loughborough applying the CPS nanoparticle size analyser

PDF Icon University of Leeds choose CPS DC24000 to enhance particle characterisation capability

PDF Icon UMPF selects CPS DC24000 to aid fluid processing research at the nanoscale

PDF Icon Analytik launches NEW Ultra High Resolution Disc Centrifuge

PDF Icon University of Liverpool choose CPS DC24000 to monitor coating thickness of drug delivery vehicles

PDF Icon University of Warwick selects CPS DC24000 for polymer colloid characterisation

PDF Icon University of Birmingham uses CPS DC24000 for bio nanoparticle analysis

PDF Icon University of Sheffield selects CPS DC24000 to analyse latexes and colloidal nanocomposite particles

PDF Icon Intertek MSG choose CPS DC24000 for nanoparticle characterisation

PDF Icon Begbroke Nano uses CPS DC24000 for nanoparticle characterisation

PDF Icon The Real Size of Your Nano Particles – A New Royal Society of Chemistry Book

Product Recommendations

“We purchased the CPS Disc Centrifuge from Analytik in 2008 expanding our range of particle and material characterisation instrumentation. The ability of the instrument to detect and measure small changes in particle size distribution enables us to determine coating thickness on particles and multi-mode particle distributions. It’s easy to use so we now have many trained users. We get great support from Analytik for servicing, extra training and answering any queries we might have about samples.”

Alison Crossley, Manager, Oxford Materials Characterisation Service

“We have been using the CPS Disc Centrifuge routinely for several years to analyze aqueous dispersions of gold nanoparticles in the 3 to 25 nm size range. It copes very well with the presence of multimodal size distributions, which usually lead to the appearance of well separated peaks. For monodisperse samples the method uniquely provides the opportunity to monitor changes in the thickness of the organic ligand shell down to the length of a single chemical bond (see Krpetic et al. ACS Nano 2013)”

Mathias Brust, Professor of Chemistry, University of Liverpool

“We are using the CPS Disc Centrifuge on daily bases to analyze the aqueous colloidal dispersions of biocides in less than 100 to 500 nm size range. The instrument operation is very easy and results are reproducible with comprehensive.”

Farnoosh Kianfar, Senior Formulation Scientist, Lonza

“Here at Intertek Wilton, we have been using the CPS Disc Centrifuge to provide a particle sizing service to a wide range of industries including Pharmaceutical and Materials based businesses. This instrument should be an essential part of any laboratory where particle sizing is performed as it enables accurate measurement of particles where other techniques (e.g., laser diffraction and PCS) run into difficulties due to size and concentration, I’d also recommend Analytik because of their unceasing support whenever we require advice on running materials we have never encountered before. ”

Jonathan Whitehead, Senior Experimental Scientist, Intertek Testing Services

“Before we purchased our CPS we routinely analysed samples by DLS. While sample analysis is not as straight forward as with our DLS instrument (it requires you to build a sucrose gradient inside the disc prior to analysis, where with our DLS instrument you just insert the cuvette and press go) the resolution far surpasses what we were used to, and is well worth the little extra effort. We routinely analyse samples looking to detect the level at which influenza virus particles may be present. ”

Kevin Murphy, Technical Specialist, Novartis Vaccines and Diagnostics

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